IDENTIFICATION OF A BROAD SARBECOVIRUS NEUTRALIZING ANTIBODY TARGETING A CONSERVED EPITOPE ON THE RECEPTOR-BINDING DOMAIN

Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain

Summary: Omicron, as the emerging variant with enhanced vaccine tolerance, has sharply disrupted most therapeutic antibodies.Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) belongs to the subgenus Sarbecovirus, members of Human Hair Blend Wig which share high sequence similarity.Herein, we report one sarbecovirus antibody, 5817, which

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Thin viscoelastic disc subjected to radial non-stationary loading

The investigation of non-stationary wave phenomena in isotropic viscoelastic solids using analytical approaches is the aim of this paper.Concretely, the problem of a thin homogeneous disc subjected to radial Industrial:Restaurant pressure load nonzero on the part of its rim is solved.The external excitation is described by the Heaviside function in

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